IVF to Overcome Recurrent Miscarriages

Mom's birth after prior miscarriage

IVF is an excellent option for couples with unexplained recurrent miscarriages. In cases in which I cannot pinpoint an etiology for the condition, I often recommend this approach. This is an important consideration at Fertility & Lifespan Medical Institute. The goal is to make sure that my patient can carry her pregnancy to term.

In cases where recurrent miscarriage is due to chromosomal abnormalities, IVF with preimplantation genetic testing (PGT-A) is beneficial. This process allows us to select the best embryos, i.e., those with no chromosomal abnormalities. This would improve the chance of a successful pregnancy.

One of the most important and distinct advantages of IVF is that it eliminates any negative effects of pelvic inflammation. This is because the egg is fertilized outside of the pelvis and the embryo transfer occurs outside of the uterus. Additionally, IVF can overcome ovulation disorders and PCOS, as well as tubal factor infertility, to reduce miscarriages.

Patients with recurrent miscarriages in association with endometriosis can benefit from IVF. Implants of endometriosis are associated with inflammation, increased oxidation, and exposure to cytotoxic chemicals. In vitro fertilization and embryo transfer eliminates the exposure of the egg or embryo to these factors.

In the uncommon cases where male factor infertility is the underlying cause of recurrent miscarriage, I recommend IVF with intracytoplasmic sperm injection (ICSI). Since this involves the injection of a single sperm directly into the egg, it facilitates the likelihood of fertilization. We can then test the resulting embryo for chromosomal abnormalities, and improve the chances of a successful pregnancy.

IVF allows us to determine the quality of embryos. If the embryo is excellent and has a normal number of chromosomes, then the failure to implant could indicate a hostile uterine environment, an immune disorder, or a clotting condition, which requires more intensive therapy.

IVF has both therapeutic and diagnostic advantages. It can identify problems in virtually all aspects of the reproductive process. Remarkably, it provides a way to identify the quality of eggs, the chromatin of sperm, fertilization, embryonic growth, chromosomal abnormalities, and implantation. Consequently, it is invaluable in situations in which recurrent miscarriages remain unexplained, and basic treatments fail.

Call the Infertility and Lifespan Medical Institute to schedule an appointment with Steven A. Brody, M.D., Ph.D.; Our Medical Director. Dr. Brody, authored the definitive textbook of IVF. He will review all of the pertinent factors relating to your fertility. All of the resources for assisted reproduction are available to help you achieve a healthy pregnancy, with the birth of your beautiful baby.

Dr. Steven A. Brody Dr. Steven A. Brody, the Director of the Infertility & Lifespan Medical Institute in San Diego, has spent his professional career providing compassionate and specialized care to help families overcome infertility. Dr. Brody has authored two textbooks, one at Stanford and one with a Nobel Prize winner at Cambridge, entitled “Principles and Practice of Assisted Human Reproduction.” Dr. Brody earned his M.D. degree at Washington University and continued his education with an internship at Yale, a residency at Stanford, and a fellowship at Baylor. Dr. Brody is the only doctor in the U.S. who has achieved Board Certifications in four distinct specialty areas including: Internal Medicine, Endocrinology & Metabolism, Obstetrics & Gynecology, and Reproductive Endocrinology & Infertility. If you are looking for a compassionate and thorough physician who works with you to overcome infertility and treat any reproductive disorders, call the office or book an appointment online today.

You Might Also Enjoy...

Mother and Baby

How Can We Determine Egg Quality?

Success with IVF ultimately depends on the maturity and the genetic composition of the eggs obtained during an IVF cycle. Fortunately, in advance of an IVF cycle, we can ascertain the quality of a woman's eggs by noninvasive testing.

Will IVF Help to Overcome Endometriosis?

Endometriosis can affect fertility in both anatomic, hormonal and biochemical ways. Endometriosis affects an estimated 20-40% of women. Overall, with endometriosis the pregnancy rates can be increased by 10 to 25% by utilizing in vitro fertilization.

IVF Using Donated Eggs

Assisted Reproductive Technologies can help virtually anyone to achieve a successful pregnancy. In some cases an egg donor is either requested or desired. Success rates are extraordinary. This information is invaluable for selected couples.

Can You Have IVF Babies at Any Age?

Women who are having difficulty in achieving pregnancy should not be discouraged. For many couples there is a situation of subfertility in which simpler interventions prove to be successful. At any age various procedures provide success.